The Department was established in 1959 with the efforts of Sri. Masood Yazdani, Sri. B. P. Shenoy and Sri. K. Raghava Reddy. Initially it offered a Post-Graduate Diploma and a Post-matriculation Certificate in Library Science. The Certificate Course was given up in 1962 following the recommendation of Sinha Committee appointed by the Government of India.

The Diploma was replaced by a postgraduate degree course in Library Science (BLISc) in 1965. The Department was renamed as Department of Library & Information Science in mid -80's as per the UGC directive. The Master's degree program (MLISc) was started in 1978-80 and the M.Phil Program was introduced during 1993-94. The Department introduced PG.Diploma in Digital Information Management (PGDDIM) Programme (2 Semester) from the academic year 2010-11.

From 2017-18 academic year 2 year M.Lib.I.Sc is Introduced and one year BLISc is discontinued .earliear to this in year academic year 2013-14 two years M.Lib.I.Sc (Integrated) Course was instituted at Jogipet PG Center in Medak District. Distinguished academicians and Librarians like Sri. Masood Yazdani, Sri. B. P. Shenoy and Sri. K. Raghava Reddy, Smt. Malathi Reddy, Sri.R.K Gupta, Sri Abdul Mahamood, Prof. M.V.Venugopal, Prof. A.A.N.Raju and Prof. J.Yadagiri Reddy, and Prof. N. Laxman Rao, Prof. S.Sudarshan Rao, Prof. V. Vishwa Mohan have served as Heads of the Department. Prof. A.A, N Raju also served as Dean, Faculty of Social Sciences and he was also UGC Emeritus Fellow .Prof. N.LaxmanRao and Prof. S.Sudarshan Rao wer also UGC Emeritus Fellows in the Deaprtment.The Department has awarded 42 Ph.D and 11 M.Phil Degrees. The Departments Awards Sri K. Ragava Reddy Gold Medal and Academy of Library Science and Documentation Gold Medal, every year to the topper in MLISc and BLISc Courses respectively. Sri C. Ramachendra Reddy Memorial Gold Medal which is instituted from the academic year 2008-09, is Awarded to the topper in Library management in BLISc. The Department offers outreach and extension Services, and organizes campus placements. Continuing and professional upgrading programs such as Seminars, Conferences, Workshops, and Refresher Courses.